In this review published in “Nature Reviews Microbiology” (IF=34.65), Johansen, Herrmann and Kremer discuss the infection process, host interactions, mechanisms of drug resistance and drug development in M. abscessus.

The team “Cell biology of bacterial infections” has demonstrated that the bacterial effector protein CvpF stimulates autophagy and promotes the anchoring of LC3B-II to Coxiella burnetii’s replicative niche, by deriving the function of the RAB GTPase RAB26.

In a work published in Science Advances (IF=12.8), Sébastien Nisole and collaborators unveil a new mechanism for the regulation of the interferon response in plasmacytoid dendritic cells (pDCs).

An ERC Proof Of Concept grant awarded to Caroline Goujon for the Flu-Attack project led by Olivier Moncorge at IRIM, in the "Interferon and Antiviral Restriction" team.

In a work published in Nature Microbiology (IF=14.6), Nathalie Arhel and collaborators reveal how HIV-1 uncoating and nuclear import are coordinated by a nuclear pore transport protein, Transportin-1 (TRN-1).

The work of Delphine Muriaux and Cyril Favard about HIV-1 assembly published in Science Advances (IF=12.8).

Raphaël Gaudin publishes his work in Nature Communications (IF=11.9). The work performed in the Raphaël Gaudin’s team at the IRIM brought to light the capacity of the virus to hide in monocytes and force them to migrate toward the brain in order to facilitate its passage through this impermeable barrier.

Laurent Kremer, leader of the IRIM team “Mycobacterial Pathogenesis and Novel Therapeutic Targets”, laureate of the European Respiratory Society Research Award: Innovation In Non-Tuberculous Mycobacteria Science And Medicine 2019

The Membrane Domains and Viral Assembly team (D. Muriaux / C. Favard) is leading a collaborative project with the CONCEPT

Raphaël GAUDIN, in collaboration with Jean-Pierre Vartanian’s team of Institut Pasteur, publishes an article in Nature Microbiology: https://www.nature.com/articles/s41564-019-0405-x

The Australian-French Association for Research and Innovation (*AFRAN) has awarded $25,000 in grants to support member-led collaborative initiatives tackling major societal issues facing Australia and France.

Type 1 interferon induces a potent antiviral state through the regulation of hundreds of interferon-stimulated genes (ISGs).