In a work published in Nature Microbiology (IF=14.6), Nathalie Arhel and collaborators reveal how HIV-1 uncoating and nuclear import are coordinated by a nuclear pore transport protein, Transportin-1 (TRN-1).

The work of Delphine Muriaux and Cyril Favard about HIV-1 assembly published in Science Advances (IF=12.8).

Raphaël Gaudin publishes his work in Nature Communications (IF=11.9). The work performed in the Raphaël Gaudin’s team at the IRIM brought to light the capacity of the virus to hide in monocytes and force them to migrate toward the brain in order to facilitate its passage through this impermeable barrier.

Laurent Kremer, leader of the IRIM team “Mycobacterial Pathogenesis and Novel Therapeutic Targets”, laureate of the European Respiratory Society Research Award: Innovation In Non-Tuberculous Mycobacteria Science And Medicine 2019

The Membrane Domains and Viral Assembly team (D. Muriaux / C. Favard) is leading a collaborative project with the CONCEPT

Raphaël GAUDIN, in collaboration with Jean-Pierre Vartanian’s team of Institut Pasteur, publishes an article in Nature Microbiology: https://www.nature.com/articles/s41564-019-0405-x

The Australian-French Association for Research and Innovation (*AFRAN) has awarded $25,000 in grants to support member-led collaborative initiatives tackling major societal issues facing Australia and France.

Type 1 interferon induces a potent antiviral state through the regulation of hundreds of interferon-stimulated genes (ISGs).

IRIM is not superstitious and proves it by welcoming Raphaël GAUDIN (CR-CN at CNRS) and his ATIP-Avenir team. Welcome to IRIM!

Autophagy is a cellular process allowing the elimination or the recycling of intracellular components. It is an ubiquitous and constitutive catabolic pathway highly conserved in eukaryotes.

Bruno BEAUMELLE publishes an article in Nature Communications (IF=12.35):  Cyclophilin A enables specific HIV-1 Tat palmitoylation and accumulation in uninfected cells (Chopard et al, 2018)

Konstantin BRODOLIN publishes an article in Science Advances (IF=11.5): Single-molecule analysis reveals the mechanism of transcription activation in Mycobacterium tuberculosis (Vishwakarma et al, 2018)