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Ouahrani Bettache Safia


Position

Engineer, IEHC INSERM

 

Team

Bacterial pathogeny and anti-infectious strategies

 

Contact

email : safia.bettache(at)irim.cnrs.fr

Tél : 04 34 35 94 51

 

Publications

Ouahrani-Bettache S, Jiménez de Bagüés MP, Jorge De La Garza, Freddi L, Juan P. Buezo, Sebastien Lyonnais, Al Dahouk, de Biase D, Köhler S, Occhialini A. Lethality of Brucella microti in a murine modele of infection depends on the wbkE gene involved in O-polysaccharide synthesis. Virulence, 2019, 10: 268-278.

Abdou E, Jiménez de Bagüés MP, Martínez-Abadía I, Ouahrani-Bettache S, Pantesco V, Occhialini A, Al Dahouk S, Köhler S, Jubier-Maurin V. RegA plays a key role in oxygen-dependent establishment of persistence and in isocitrate lyase activity, a critical determinant of in vivo Brucella suis pathogenicity. Front Cell Infect Microbiol, 2017, 7: 186.

Köhler S, Ouahrani-Bettache S, Winum JY. Brucella suis carbonic anhydrases and their inhibitors: Towards alternative antibiotics? J Enzyme Inhib Med Chem, 2017, 32: 683-687.

Riafrecha L, Vullo D, Ouahrani-Bettache S, Köhler S, Dumy P,  Winum JY,   Supuran CT, Colinas PA. Inhibition of b-carbonic anhydrases from Brucella suis with C-cinnamoyl glycosides incorporating the phenol moiety. J Enzyme Inhib Med Chem, 2015, 30:1017-1020.

Turtaut F, Lopez M, Ouahrani-Bettache S, Köhler S, Winum JY. Oxo & thiooxo pyrimidine, a protection tool in the synthesis of histidine analogues. Bioorg Med Chem Lett. 2014, 24: 5008-5010

Dambrosio K, Lopez M, Datha NA, Ouahrani-Bettache S, Köhler S, Ascione G,  Monti SM, Winum JY, De Simone G. The crystal structure of HDH of B suis. Biochimie. 2014, 97: 114-120

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IRIM
Institut de Recherche en Infectiologie de Montpellier
UMR 9004 - CNRS / UM
1919 route de Mende - 34293 Montpellier cedex 5
FRANCE

 

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